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Emergencias (St. Vicenç dels Horts) ; 24(4): 277-281, ago. 2012. tab
Artigo em Espanhol | IBECS | ID: ibc-104029

RESUMO

Objetivo: Las enfermedades generadas por el virus varicela zóster en el adulto, varicela y herpes zóster (HZ), sólo ocasionalmente tienen un curso grave. Se plantea la identificación de marcadores de gravedad en los pacientes adultos atendidos en los servicios de urgencias hospitalarios a través de la necesidad de ingreso hospitatalario. Método: El registro multicéntrico de pacientes adultos con infecciones por virus varicela zóster atendidos en servicios de urgencias (REVIVAZ) se usó para la identificación de factores asociados a gravedad. Mediante un análisis univariable se identificaron los factores de comorbilidad y clínicos que se asociaron al ingreso en cada una de las dos formas de la enfermedad .Resultados: Durante los años 2009 y 2010 se han registrado 363 casos de varicela y1.240 de HZ. El porcentaje de pacientes adultos ingresados con varicela fue el 6,9% y con HZ el 4,2%. Los casos de varicela que tenían tratamiento inmunosupresor ingresaron en el 71% (p < 0,01 respecto al resto), los que presentaban clínica de dolor torácico, tos y disnea fueron ingresados en el 38,9%, 22,8% y 66,7% respectivamente(p < 0,01 respecto al resto para cada uno de ellos). Los casos de HZ ingresados lo fueron en el 53,8% por patologías asociadas y la enfermedad pulmonar obstructiva crónica (EPOC) estuvo presente en el 82,4% de los pacientes. Los casos de HZ con fiebre, escalofríos y mialgias ingresaron en el 27,2%, 18,3%, y 11,9%, respectivamente(p < 0,01 respecto del resto para cada uno de ellos). El porcentaje de ingreso con (..) (AU)


Background and objective: Diseases caused by the varicella-herpes virus in adults (chicken pox and shingles) only occasionally become serious. We sought markers that could be used in the hospital emergency department to identify adults with serious infections requiring admission. Methods: The REVAVAZ multicenter register of adults with varicella-zoster virus infections who came to hospital emergency departments for care was used to identify variables associated with severity. Clinical and comorbidity factors underwent univariate analysis to detect attributes associated with admission in each varicella-herpes virus disease. Results: A total of 363 cases of chicken pox and 1240 cases of Herpes Zoster were registered in 2009 and 2010; 6.9% of the adults with chicken pox and 4.2% of the adults with Herpes Zoster were admitted. Among patients with chickenpox, 71% of those under immunosuppressive treatment were admitted (P<.01); 38.9% of those with chest pain, 22.8%of those with cough, and 66.7% of those with shortness of breath were admitted (P<.01). Among patients with Herpes Zoster, 53.8% were admitted for concomitant diseases; 82.4% of the patients with chronic obstructive pulmonary disease were hospitalized. Also admitted with Herpes Zoster were 27.2% of those with fever, 18.3% of those with chills, and 11.9% of those with muscle pain (P<.01). A total of 45.5% of those with neuropathy, 57.1% with respiratory disease, and 64.3% with disseminated varicella-herpes virus disease (P<.01) were admitted. Conclusions: Adults with more severe chicken pox infections are those with respiratory symptoms and under immunosuppressive therapy. Patients with Herpes Zoster are admitted because of exacerbation of some concomitant disease process, especially COPD; Herpes Zoster symptoms are usually more severe in these patients (AU)


Assuntos
Humanos , Biomarcadores/análise , Varicela/complicações , Herpesvirus Humano 3/patogenicidade , Herpes Zoster/complicações , Índice de Gravidade de Doença , Fatores de Risco , Comorbidade
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